A lire en août...

- Rôle des gènes Olig1 et Olig2 dans la trisomie 21.

- Les mutations de TUBA1A causent différents types de lissencéphalie.

- Analyze du transcriptome dans des cellules 'Rett' clonées.

Jean-Christophe Roux - Publications

2010

Progressive motor and respiratory metabolism deficits in post-weaning Mecp2-null male mice.

Pratte M, Panayotis N, Ghata A, Villard L, Roux JC.

Behavioural Brain Research, 2010, sous presse.



Biogenic amines in Rett syndrome : the usual suspects.

Roux JC, Villard L.

Behavior Genetics, 2010, 40:55-75.



Progressive noradregernic deficits in the locus coeruleus of the Mecp2 deficient mouse.

Roux JC, Panayotis N, Dura E, Villard L.

Journal of Neuroscience Research, 2010, 88:1500-1509.



2009

Spatiotemporal expression in mouse brain of Kiaa2022, a gene disrupted in two patients with severe mental retardation.

Cantagrel V, Haddad MR, Ciofi P, Andrieu D, Lossi AM, van Maldergem L, Roux JC, Villard L.

Gene Expression Patterns, 2009, 9:423-429.



2008

Expression of methyl-CpG binding protein 2 (Mecp2) during the postnatal development of the mouse brainstem.

Dura E, Villard L, Roux JC.

Brain Research, 2008, 1236:176-184.


Tyrosine hydroxylase deficit in the chemoafferent and the sympathoadrenergic pathways of the Mecp2 deficient mouse.

Roux JC, Dura E, Villard L.

Neuroscience Letters, 2008, 447:82-86.


2007

Pharmacological treatment of Rett syndrome improve breathing and survival in a mouse model.

Roux JC, Villard L.

Médecine & Sciences, 2007, 23:805-807.


Developmental plasticity of the carotid chemoafferent pathway in rats that are hypoxic during the prenatal period.

Peyronnet J, Roux JC, Mamet J, Perrin D, Lachuer J, Pequignot JM, Dalmaz Y.

European Journal of Neuroscience, 2007, 26:2865-2872.


Treatment with desipramine improves breathing and survival in a mouse model for Rett syndrome.

Roux JC, Dura E, Moncla A, Mancini J, Villard L.

European Journal of Neuroscience, 2007, 25:1915-1922.


2006

Noradrenaline deficiency as the origin of respiratory disorders in an animal model of Rett syndrome.

Villard L, Roux JC.

Médecine & Sciences, 2006, 22:81-83.


Possible modulation of the mouse respiratory rhythm generator by A1/C1 neurones.

Zanella S, Roux JC, Viemari JC, Hilaire G.

Respiratory Physiology and Neurobiology, 2006, 153:126-138.



2005

Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice : implications for Rett syndrome.

Roux JC, Viemari JC, Tryba AK, Saywell V, Burnet H, Pena F, Zanella S, Bévengut M, Barthélémy-Requin M, Herzing LB, Moncla A, Mancini J, Ramirez JM, Villard L, Hilaire G.

Journal of Neuroscience, 2005, 25:11521-11530.


Developmental changes in HIF transcription factor in carotid body: relevance for O2 sensing by chemoreceptors.

Roux JC, Brismar H, Aperia A, Lagercrantz H.

Pediatric Research, 2005, 58:53-57.



Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function.

Cohen G, Roux JC, Grailhe R, Malcolm G, Changeux JP, Lagercrantz H.

Proc Natl Acad Sci USA, 2005, 102:3817-3821.



2004

Chemosensory inputs and neural remodeling in carotid body and brainstem catecholaminergic cells.

Soulage C, Pascual O, Roux JC, Denavit-Saubie M, Pequignot JM.

Advances in Experimental Medicine and Biology, 2004, 551:53-58.



Long-term prenatal hypoxia alters maturation of brain catecholaminergic systems and motor behavior in rats.

Perrin D, Mamet J, Scarna H, Roux JC, Berod A, Dalmaz Y.

Synapse, 2004, 54:92-101.



Carotid chemodenervation approach to study oxygen sensing in brain stem catecholaminergic cells.

Pascual O, Roux JC, Soulage C, Morin-Surun MP, Denavit-Saubie M, Pequignot JM.

Methods in Enzymology, 2004, 381:422-449.



Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice.

Nsegbe E, Wallen-Mackenzie A, Dauger S, Roux JC, Shvarev Y, Lagercrantz H, Perlmann T, Herlenius E.

Journal of Physiology, 2004, 556:43-59.



2003

Prenatal hypoxia and early postnatal maturation of the chemoafferent pathway.

Peyronnet J, Roux JC, Perrin D, Pequignot JM, Lagercrantz H, Dalmaz Y.

Advances in Experimental Medicine and Biology, 2003, 536:525-533.



Neurochemical development of the brainstem catecholaminergic cell groups in rat.

Roux JC, Mamet J, Perrin D, Peyronnet J, Royer C, Cottet-Emard JM, Pequignot JM, Dalmaz Y.

Journal of Neural Transmission, 2003, 110:51-65.



2002

Long-lasting adverse effects of prenatal hypoxia on developing autonomic nervous system and cardiovascular parameters in rats.

Peyronnet J, Dalmaz Y, Ehrstrom M, Mamet J, Roux JC, Pequignot JM, Thoren HP, Lagercrantz H.

Pflugers Archives, 2002, 443:858-865.



Long-term prenatal hypoxia alters maturation of adrenal medulla in rat.

Mamet J, Peyronnet J, Roux JC, Perrin D, Cottet-Emard JM, Pequignot JM, Lagercrantz H, Dalmaz Y.

Pediatric Research, 2002, 51:207-214.



2000

O2-sensing after carotid chemodenervation: hypoxic ventilatory responsiveness and upregulation of tyrosine hydroxylase mRNA in brainstem catecholaminergic cells.

Roux JC, Pequignot JM, Dumas S, Pascual O, Ghilini G, Pequignot J, Mallet J, Denavit-Saubie M.

European Journal of Neuroscience, 2000, 12:3181-3190.



Neurochemical reorganization of O2 chemoreflex pathway after carotid body denervation in rats.

Roux JC, Peyronnet J, Pascual O, Dalmaz Y, Pequignot JM.

Advances in Experimental Medicine and Biology, 2000, 475:823-828.



Prenatal hypoxia impairs the postnatal development of neural and functional chemoafferent pathway in rat.

Peyronnet J, Roux JC, Geloen A, Tang LQ, Pequignot JM, Lagercrantz H, Dalmaz Y.

Journal of Physiology, 2000, 524:525-537.



Ventilatory and central neurochemical reorganisation of O2 chemoreflex after carotid sinus nerve transection in rat.

Roux JC, Peyronnet J, Pascual O, Dalmaz Y, Pequignot JM.

Journal of Physiology, 2000, 522:493-501.